These ENOVA COST Action funded training Schools will provide participants with both theoretical and practical insights into vaccines and vaccine adjuvants. They will be held at locations of ENOVA members and will host 12 to 15 early stage researchers. Individual Training Schools will be announced on this page over the course of the ENOVA Cost Action.
When a Call to apply opens for an individual Training School, the applicants will be asked to submit a short CV and letter of motivation before a given deadline.
The letter of motivation should provide a clear indication of the applicant’s experience as it relates to the topic of the Training School: why the applicant is interested in the Training School and how it will contribute to his or her learning, career and research objectives.
Researchers at different levels will be eligible to apply to the Training Schools (PhD students, post-doctoral researchers, research managers). Priority will be given to early stage researchers and to trainees from inclusiveness target countries. Participants will also be gender-balanced.
The Training Schools will be fully funded by the ENOVA COST Action. A grant will be provided for the accepted participants as a contribution to the travelling costs, accommodation and subsistence during the Training School. Details of the amount of the grant will be announced when individual Training Schools are called.
Theoretical course on Adjuvants and Vaccine Formulation
25-28 March 2019, Geneva, Switzerland, organised by Vaccine Formulation Institute, in collaboration with TRANSVAC2
The course provides an overview of state-of-the-art adjuvant systems and addresses the preclinical and clinical development of adjuvanted vaccines. It combines interactive theoretical parts (lectures and discussion rounds) with practical parts where participants work on different thematic case studies. Invited trainers will present the various adjuvant systems, such as Aluminum salts, Oil-in-Water emulsions, Water-in-Oil emulsions, Liposomes, PLGA particles, Virosomes, QS21, TLR ligands, as well as aspects of preclinical and clinical development of adjuvanted vaccines.For the practical parts, participants will be split into smaller groups. Each group will work on one case study, facilitated by a trainer. The trainer will introduce the case study, provide background information, and explain the tasks and questions for the group work. Following this introduction, each group will work independently on their case study for a given time and will prepare a summary of the case that will be presented to all participants at the end.
The course will be open to 20 participants, 10 participants will be selected by ENOVA and 10 by TRANSVAC2.
Immunoactive carbohydrates and glycolipids: how to obtain them from Nature and how to build them in the lab
2-4 April 2019, Napoli, Italy, organised by University of Napoli Federico II
The Training School will be entitled “Immunoactive carbohydrates and glycolipids: how to obtain them from Nature and how to build them in the lab”. It will consist of oral lessons on the analytical and organic chemistry techniques most frequently employed in research labs in the frame of the discovery of new immunomodulators. The training school will be divided into two subjects. Approximately 50% of the lessons will be devoted to the description of i) extraction and purification protocols for collecting potentially immunoactive carbohydrates and glycolipids from different natural sources (Gram negative bacteria, marine organisms, plants), and ii) structural characterization methods for a detailed elucidation of the chemical structure of the isolated biomolecules. The second subject of the training school will be focused on the two different approaches – total synthesis and semisynthesis – that are commonly employed
for the obtainment of synthetic immunomodulators, that resemble or mimic the natural carbohydrate and glycolipid immunoactive species. A hands‐on session will be also scheduled with simulation of isolation and structure determination of natural products and, likewise, another one with simulation of conceiving a total synthesis of a new glycolipid based immunoadjuvant. 2 trainers will be reimbursed by ENOVA, the remaining will be local trainers.
The course will be open to 20 participants selected by ENOVA